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Michelle Prudhomme Selected Research

rebeccamycin

12/2008Rebeccamycin derivatives as dual DNA-damaging agents and potent checkpoint kinase 1 inhibitors.
10/2005Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework.
8/2003Rebeccamycin analogues bearing amine substituents or other groups on the sugar moiety.
2/2003Rebeccamycin analogues as anti-cancer agents.

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Michelle Prudhomme Research Topics

Disease

11Neoplasms (Cancer)
08/2011 - 02/2003
5Carcinoma (Carcinomatosis)
04/2008 - 10/2005
5Leukemia L1210
04/2008 - 10/2005
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
09/2007 - 10/2005
1Hematologic Neoplasms (Hematological Malignancy)
10/2010
1Tetraploidy
12/2007
1Poisoning
08/2003

Drug/Important Bio-Agent (IBA)

5Phosphotransferases (Kinase)IBA
10/2010 - 09/2007
4Checkpoint Kinase 1IBA
08/2011 - 09/2007
4rebeccamycinIBA
12/2008 - 02/2003
2Protein Kinases (Protein Kinase)IBA
08/2011 - 09/2008
2Antineoplastic Agents (Antineoplastics)IBA
12/2008 - 08/2008
2Biological ProductsIBA
01/2006 - 08/2003
2A-Form DNA (A-DNA)IBA
01/2006 - 09/2004
2DNA (Deoxyribonucleic Acid)IBA
01/2006 - 08/2003
1Topoisomerase InhibitorsIBA
08/2011
1Pharmaceutical PreparationsIBA
10/2010
1proto-oncogene proteins pimIBA
10/2010
1Serine (L-Serine)FDA Link
10/2010
1Threonine (L-Threonine)FDA Link
10/2010
1Cyclin AIBA
09/2008
1Cisplatin (Platino)FDA LinkGeneric
12/2007
1isogranulatimideIBA
09/2007
1Aza CompoundsIBA
10/2005
1Type I DNA Topoisomerases (Topoisomerase I)IBA
08/2003

Therapy/Procedure

1Therapeutics
08/2008
1Radiotherapy
12/2007
1Drug Therapy (Chemotherapy)
12/2007